Language Performance After Mild Traumatic Brain Injury: An Event-Related Potential Study
Tara Flaugher1,2, Rocio Norman1,2, Antonio Allevato1, Jena Hermes2, Nicole Wicha1,2; 1University of Texas at San Antonio, 2University of Texas Health Science Center San Antonio
Worldwide, sixty-nine million people will sustain a traumatic brain injury (TBI) and most will be mild in severity (mTBI). Recently, public awareness of the persistent neurobehavioral symptoms (NBS) following mTBI has increased. Common NBS such as pain, slow processing speed, headache, and sleep problems have been associated with poor language performance, but the underlying neural correlates remain largely unknown. While many studies have examined non-linguistic ERP components following mTBI, few have examined language-related ERP components like the N400 and P600. To investigate linguistic processing after mTBI, we developed a self-paced reading ERP paradigm using Osterhout & Nicol (1999) stimuli to measure brain and behavioral responses to semantic and syntactically anomalous sentences from 44 community-dwelling adults with (+mTBI, n=18; Female=10) and without (-mTBI, n=26; Female=15). We will compare N400, P600 and reading time responses between groups and use NBS, sleep, and communication problems as correlates. This study will broaden the limited methodological knowledge of self-paced reading ERP paradigms, begin to clarify the effects of mTBI on language function, and set a baseline for future ERPs to investigate language processing in mTBI.
Topic Areas: Disorders: Acquired, Reading